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Kala-Azar: Oral Nano Medicine

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    Science & Technology
  • Published
    24th Aug, 2020
  • Scientists from the Institute of Nano Science & Technology Mohali have developed an oral Nano medicine for Kala-Azar.
  • Kala- Azar is one of the most neglected tropical diseases.
  • The oral Nano medicine is manufactured with the help of surface-modified solid lipid nanoparticles based combinational cargo system for combating the disease.
  • The solid lipid nanoparticles (SLNs) can help enhance the oral uptake of the therapeutic agent by retaining a solubilized state of the drug in the Gastrointestinal Tract.
  • The oral therapeutics is expected to help in the control and its elimination.
  • Visceral leishmaniasis or kala-azar is a slow progressing Neglected Tropical Disease caused by a protozoan parasite of genus Leishmania.
  • It is a zoonotic infection transmitted by the sand fly, a blood-sucking pest, found in moist (humid) mud and sand and close to livestock.
  • The parasite primarily infects the reticuloendothelial system and may be found in abundance in bone marrow, spleen and liver.
  • It is the second-largest parasitic killer in the world after Malaria.

Verifying, please be patient.